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目的研究放疗联合热疗治疗局部晚期非小细胞肺癌患者的临床效果及不良反应。方法选取局部晚期非小细胞肺癌患者62例,根据治疗药物不同随机分为两组各31例,对照组按照常规三维适形放疗(3D-CRT)治疗,观察组在对照组治疗方案基础上加用内生场热疗方案,对两组治疗效果进行对比分析。结果治疗结束2个月后观察组患者治疗有效率为61.29%(19/31),显著高于对照组的45.2%(14/31),差异有统计学意义(P<0.05);两组患者治疗期间不良反应发生率差异无统计学意义(P>0.05)。结论局部晚期非小细胞肺癌患者采用放疗联合热疗方案有助于提高治疗有效率,且不增加不良反应的发生,值得临床推广。
Objective To study the clinical effects and adverse reactions of radiotherapy combined with hyperthermia in the treatment of patients with locally advanced non-small cell lung cancer. Methods A total of 62 patients with locally advanced non-small cell lung cancer were randomly divided into two groups according to the treatment drugs. The control group was treated with conventional three-dimensional conformal radiotherapy (3D-CRT), and the observation group was added with the treatment group of the control group. The endogenous field hyperthermia program was used to compare the effects of the two groups. Results The effective rate of observation group was 61.29% (19/31) after 2 months of treatment, which was significantly higher than that of the control group (45.2%, 14/31). The difference was statistically significant (P<0.05); There was no significant difference in the incidence of adverse reactions during treatment (P>0.05). Conclusion Radiotherapy combined with hyperthermia in patients with locally advanced non-small cell lung cancer can increase the efficiency of treatment without increasing the incidence of adverse reactions. It is worthy of clinical promotion.