目的 :探讨分析应用植皮后封闭式负压引流术治疗Ⅲ°烧伤的临床效果。方法 :选取2013年3月~2014年4月间我院收治的Ⅲ°烧伤患者56例作为研究对象,采用随机数字表法将其分为对照组(28例)和试验组(28例),单纯采用切痂植皮的方式为对照组患者进行治疗,采用植皮后封闭式负压引流术为试验组患者进行治疗,观察对比两组患者的植皮成活率、感染率及治愈时间,并将对比的结果及两组患者的临床资料进行回顾性的分析。结果 :对照组患者的出血量为(55.6±1.2)ml/100cm2,治愈时间为(17.8±1.8)d,感染率为3.57%;试验组患者的出血量为(43.5±3.2)ml/100cm2,治愈时间为(15.2±1.1)d,感染率为0%。试验组患者的各项临床指标均明显优于对照组患者,差异显著(P<0.05),具有统计学意义。在对照组28例患者中,皮片成活情况判定等级为优的患者有24例,为中的患者有2例,为差的患者有2例;在试验组28例患者中,皮片成活情况判定等级为优的患者有27例,为中的患者有1例,为差的患者有0例。试验组患者的临床疗效明显优于对照组患者,差异显著(P<0.05),具有统计学意义。结论 :应用植皮后封闭式负压引流术治疗Ⅲ°烧伤的临床效果显著,具有出血量少、皮片成活率高、感染率低、患者的住院时间短等优点,值得在临床上推广应用。 Objective: To investigate the clinical effect of closed negative pressure drainage in the treatment of Ⅲ ° burn after skin grafting. Methods: From March 2013 to April 2014, 56 cases of Ⅲ ° burn patients treated in our hospital were selected as the research object. The patients were divided into control group (28 cases) and experimental group (28 cases) by random number table method. The method of excision and skin grafting was used to treat patients in the control group. Closed grafts were used to treat the patients in the test group. The skin graft survival rate, infection rate and cure time were compared between the two groups. Results and clinical data of two groups were retrospectively analyzed. Results: The bleeding volume of the control group was (55.6 ± 1.2) ml / 100cm2 and the healing time was (17.8 ± 1.8) d, the infection rate was 3.57%. The bleeding volume of the control group was (43.5 ± 3.2) ml / 100cm2, The cure time was (15.2 ± 1.1) d, the infection rate was 0%. The experimental group of patients with clinical indicators were significantly better than the control group patients, the difference was significant (P <0.05), with statistical significance. Among the 28 patients in the control group, there were 24 patients with superior skin survival rating, 2 patients were moderate, and 2 patients were poor; in the 28 patients in the test group, the skin survival Twenty-seven patients were rated superior, 1 patient was moderate, and 0 was poor. The clinical efficacy of the experimental group was significantly better than the control group, the difference was significant (P <0.05), with statistical significance. Conclusion: The clinical effect of closed negative pressure drainage in the treatment of Ⅲ ° burn after skin grafting is obvious. It has the advantages of less bleeding, high skin graft survival, low infection rate and shorter hospitalization time, which is worth popularizing in clinic.