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河南省黄河流域为钩端螺旋体病的低发疫区。１９９２年以来，黄河北岸广大稻田区发生本病流行。其主要表现为：１．流行形式为稻田型；流行期为４～１１月，流行高峰在８月份；临床表现复杂，以流感伤寒型为主，黄疸出血型及肺大出血型比例较高。２．疑似病例及健康人隐性感染的血清群均以黄疸出血群为主，其它有波摩拿群、秋季群等。当地优势鼠种为黑线姬鼠，其带菌率夏季为１６．６７％，秋季为２７．２７％，携带菌群主要为黄疸出血群，与人间主要流行菌群一致。３．原阳县为流行的中心地区，其流行强度明显高于毗邻的其他发病县。４．易感人群普遍接种相应型别钩体疫苗，开展以灭鼠为主的爱国卫生运动，进行疾病防治的宣传等综和防治措施，可有效地预防本病流行，降低发病率，１９９４年以后发病呈下降趋势。
The Yellow River Basin in Henan Province is a low incidence of leptospirosis. Since 1992, the epidemic of this disease has occurred in a large number of paddy fields along the north bank of the Yellow River. Its main manifestations are: 1. The epidemic form is paddy field; the epidemic period is from April to November, the epidemic peak is in August; the clinical manifestations are complex, and the predominant type is influenza typhoid, with a high proportion of bleeding and pulmonary hemorrhage. 2. Suspected cases and healthy people invisible infection of the serogroup are mainly jaundice bleeding group, the other with Bo Morandam, the autumn group. The local predominant species of Apodemus agrarius, the carrier rate of 16.67% in summer and 27.27% in autumn, carrying bacteria mainly jaundiced bleeding group, and the major epidemic strains in the world. 3. Yuanyang County as a popular central area, the intensity of its epidemic was significantly higher than the other adjacent counties. 4. Susceptible populations are generally vaccinated with the corresponding type of hooked vaccine, to carry out anti-rat patriotic health campaigns, prevention and treatment of diseases and other comprehensive prevention and control measures can effectively prevent the epidemic, reduce the incidence of morbidity after 1994 Showing a downward trend.