论文部分内容阅读
目的:探讨卵巢子宫内膜异位囊肿剥除术后宫腔放置左炔诺孕酮宫内节育器(LNG-IUS)的临床疗效。方法:选择2006年6月~2008年4月在该院施行卵巢子宫内膜异位囊肿剥除术的患者,31例为术后放置LNG-IUS(LNG-IUS组),30例为术后口服孕三烯酮(对照组),比较术前VAS>3分者治疗后VAS的评分变化及观察复发情况等。结果:LNG-IUS组平均VAS评分由术前的(6.45±0.47)分分别降至治疗3个月及6个月后的(1.65±0.36)分和(1.85±0.48)分,治疗3个月和6个月与术前VAS评分比较有统计学差异(P<0.01),但与孕三烯酮组比较差异无统计学意义(P=0.611,P=0.462);治疗1年LNG-IUS组与对照组中重度痛经的发生率分别为12.90%(4/31)和30.00%(9/30),两组复发率分别为19.35%(6/31)和33.33%(10/30),中重度痛经的发生率和复发率两组比较无统计学差异(P=0.623,P=0.255)。愿意继续接受治疗的LNG-IUS组(87.10%)明显高于对照组(46.67%),差异有统计学意义(P<0.01)。结论:LNG-IUS可有效缓解卵巢子宫内膜异位囊肿的相关疼痛,有较好的依从性,可作为内异症保守性手术后预防或延缓复发的辅助性治疗方法。
Objective: To investigate the clinical efficacy of levonorgestrel-releasing intrauterine device (LNG-IUS) after uterine endometriosis removal. Methods: A total of 31 patients with LNG-IUS (LNG-IUS group) and 30 patients with postoperative ovarian endometriosis (LNG-IUS) were selected from June 2006 to April 2008 in our hospital. Oral gestrinone (control group), VAS> 3 points before treatment compared VAS score changes and observe the recurrence and so on. Results: The average VAS score of LNG-IUS group decreased from (6.45 ± 0.47) points before treatment to (1.65 ± 0.36) points and (1.85 ± 0.48) points after 3 months and 6 months respectively, (P = 0.01), but no significant difference compared with gestrinone group (P = 0.611, P = 0.462). One year treatment with LNG-IUS group The incidence of severe dysmenorrhea in the control group was 12.90% (4/31) and 30.00% (9/30), respectively. The recurrence rates of the two groups were 19.35% (6/31) and 33.33% (10/30) There was no significant difference between the two groups in the incidence of severe dysmenorrhea and recurrence (P = 0.623, P = 0.255). The LNG-IUS group (87.10%) who were willing to continue treatment was significantly higher than the control group (46.67%), the difference was statistically significant (P <0.01). CONCLUSION: LNG-IUS can effectively relieve pain associated with ovarian endometriosis cysts and has good compliance. It can be used as an adjunctive treatment to prevent or delay relapse after conservative surgery of endometriosis.