论文部分内容阅读
目的:分析2010年度苏州大学附属第一医院药品不良反应(ADR)的发生规律,为合理用药提供参考。方法:收集2010年度604例ADR报告表,分别从药物种类、抗菌药物类别、临床表现、给药途径及患者的年龄等方面进行分析。结果:604例ADR中,涉及药品213种,其中抗菌药物49种,与抗菌药物有关的ADR最为多见,占总例数的43.71%(264/604);ADR临床表现最为常见皮肤及其附件损害,其次是消化系统损害等;严重ADR占3.64%(22/604);静脉滴注引起的ADR占56.46%(341/604)。结论:应严格掌握药物使用的适应证,合理使用抗菌药物,以减少和避免ADR的发生。
Objective: To analyze the incidence of adverse drug reactions (ADR) in the First Affiliated Hospital of Soochow University in 2010, and provide a reference for rational drug use. Methods: A total of 604 cases of ADR were collected in 2010, which were analyzed from the categories of drugs, the categories of antimicrobial drugs, clinical manifestations, route of administration and patient’s age. Results: Of the 604 ADRs, 213 kinds of drugs were involved, of which 49 were antibacterials. ADRs were the most common with antimicrobial agents, accounting for 43.71% (264/604) of the total cases. The most common clinical manifestations of ADR were skin and its appendages Damage, followed by digestive system damage; severe ADR accounted for 3.64% (22/604); ADR caused by intravenous drip accounted for 56.46% (341/604). Conclusion: The indications of drug use should be strictly controlled and antibiotics should be used reasonably to reduce and avoid the occurrence of ADR.