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Disseminated Intra-Vascular～Coagulation,简称DIC,系指弥散性的血管内血液的凝固,为了更好地理解DIC的发病机理,先复习与血液凝固过程有关的一些生理、生化基本概念。 (一)、血液在血管中保持流动状态的机理:首先,机体内有完整的抗凝系统:体内凝血系统和纤溶系统处于矛盾的统一体中,凝血系统激活的同时,纤溶系统也被激活,这两个对血液凝固作用相反的系统,相互制约保持着动态平衡,使血液处于流动状态。但一般情况下,是凝血过程的激活才使纤溶系统激活。此外,血液中还有一些抗凝物质和凝血抑制因
Disseminated Intra-Vascular ~ Coagulation, referred to as DIC, refers to disseminated intravascular blood coagulation, in order to better understand the pathogenesis of DIC, review the blood coagulation process and some of the basic physiological and biochemical concepts. First, the body has a complete anticoagulant system: the body coagulation system and fibrinolytic system in a contradictory unity, the activation of the coagulation system, fibrinolytic system is also Activation, the two systems that have the opposite effects on blood coagulation, keep the homeostasis in each other and keep the blood flowing. However, in general, activation of the coagulation process activates the fibrinolytic system. In addition, there are some anticoagulants and coagulation inhibitors in the blood