脑出血并发多器官功能衰竭时外周血T细胞亚群的改变

来源 :卒中与神经疾病 | 被引量 : 0次 | 上传用户:lijing1671
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检测脑出血并发多器官功能衰竭(MOF)患者外周血T细胞亚群的变化,发现其值比正常人明显降低,它们分别是CD+340.61±4.53,CD+428.36±4.71,CD+823.22±6.76,影响T细胞亚群改变的原因主要是由于脑出血引起脑水肿,破坏了儿茶酚胺与多巴胺的分泌,影响了T细胞的生成与激活;另外,脑出血对呼吸中枢的影响及并发肺部感染致缺氧和二氧化碳潴留也影响T细胞亚群的生成。 The changes of T lymphocyte subsets in peripheral blood of patients with intracerebral hemorrhage complicated with multiple organ failure (MOF) were significantly lower than those in normal controls (CD + 340.61 ± 4.53, CD + 428.36 ± 4.71, CD + 823 .22 ± 6.76. The main reason for the change of T cell subsets was cerebral edema caused by intracerebral hemorrhage, which destroyed the secretion of catecholamines and dopamine and affected the generation and activation of T cells. In addition, the influence of cerebral hemorrhage on respiratory center And concurrent lung infection caused by hypoxia and carbon dioxide retention also affect the generation of T cell subsets.
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