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本文用取自四川、金州、芒崖和涞源四个温石棉矿的样品对大鼠作胸腔注入染尘,以探讨不同产地温石棉的致癌力。实验另设一个玻璃棉组和生理盐水对照组。实验结果表明,四个石棉组胸膜间皮瘤诱发率为8.51~41.67%,玻璃棉组26.67%,对照组未发生间皮瘤。川棉、金棉、芒棉及玻棉组之间间皮瘤诱发率无显著差异,但均明显高于涞棉及生理盐水对照组,而后两组之间无显著差异,原因有待进一步探讨。
In this paper, four samples of chrysotile from Sichuan, Jinzhou, Mangya and Huangyuan were used to infect the rats with thoracic cavity to investigate the carcinogenicity of chrysotile in different areas. The experiment set up a glass wool group and saline control group. The experimental results showed that the inducing rate of pleural mesothelioma was 8.51 ~ 41.67% in four asbestos groups and 26.67% in glass wool group, while no mesothelioma occurred in the control group. There was no significant difference in the induction rates of mesothelioma between the two groups, but they were all significantly higher than that of the control group and there was no significant difference between the two groups. The reason for further discussion.