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The electrospinning process was applied to fabricate the nanofibers of biodegradable poly(ε-caprolactone) (PCL) in which different contents of multiwalled carbon nanotubes (MWCNTs) were embedded.Afterward,the electrospun nanofibers were successfully decorated with shish-kebab structure via a self-induced crystallization technique.The topographical features and the mechanical properties of the composite scaffolds were characterized,and the biocompatibility of the material was assessed by using human osteogenic sarcoma osteoblasts (MG-63 cells).The carbon nanotube (CNT) concentration is found to affect the fiber diameter and mechanical properties of electrospun nanofibers and the periodic distance of the shish-kebab architecture.Cellular attachment and proliferation assays reveal that 0.5 wt％ CNT-embedded PCL scaffold shows enhanced biocompatibility with MG-63 cells than their counterparts made of neat PCL,and the collagen-like nanotopology provided by the shish-kebab structure further facilitates the cell adhesion and proliferation.The superior interactions between cells and scaffolds demonstrate that the shish-kebab-structured CNTs/PCL nanofibers may be promising candidate for tissue engineering scaffold application.