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目的观察女性糖尿病患者绝经前、后组血清胱抑素C、肌酐及血脂含量变化。方法糖尿病患者46例均为女性,分为绝经前组(21例)、绝经后组(25例),测定晨起空腹静脉血胱抑素C、肌酐、空腹血糖、糖化血红蛋白、总胆固醇、三酰甘油,对两组各指标进行分析。结果绝经后组胱抑素C、总胆固醇、三酰甘油高于绝经前组,两组比较有统计学意义(P<0.05);而血糖、肌酐、糖化血红蛋白绝经前后无变化。结论女性糖尿病患者绝经后胱抑素C、总胆固醇、三酰甘油增高。
Objective To observe the changes of serum cystatin C, creatinine and blood lipid in premenopausal and postmenopausal women with diabetes. Methods All 46 diabetic patients were divided into premenopausal group (21 cases) and postmenopausal group (25 cases). The fasting venous cystatin C, creatinine, fasting blood glucose, glycosylated hemoglobin, total cholesterol, Acylglycerol, the two groups of indicators for analysis. Results The postmenopausal group had higher levels of cystatin C, total cholesterol and triglyceride than those of the premenopausal group (P <0.05), while no changes in blood glucose, creatinine and glycosylated hemoglobin before and after menopause. Conclusions Postmenopausal women with elevated levels of cystatin C, total cholesterol and triglyceride in diabetic patients.