喉部恶性病变主要是鳞状上皮癌,治疗方式包括手术、放疗、同步放化疗等。20世纪70年代初Strong和Jako[1]将CO2激光应用于喉显微外科手术治疗声门型喉癌,1978年Vaughan报道了激光治疗喉癌声门上型的结果,此后激光手术迅速发展,在一些发达国家已占全部喉癌手术的30%～50%,呈逐年增长趋势。喉部激光手术的优势在于损伤小、功能保全好、恢复快、手术时间短及费用低等,另外有报道显示激光手术能保持血红蛋白水平,有利于术后放疗[2]。1手术适应证由于设备技术和认识差异,尚无标准的手术适应证。理论上支撑喉镜下所暴露的组织结构均可用激光切除,在保留软骨框架的同时能完成喉垂直部分切除术和声门上水平切除术[3],但实际操作时会受到某些客观因素的 Malignant laryngeal lesions are mainly squamous cell carcinoma, treatment methods include surgery, radiotherapy, concurrent radiotherapy and chemotherapy. In the early 1970s, Strong and Jako [1] applied CO2 laser to laryngeal microsurgery for the treatment of glottic laryngeal cancer. In 1978, Vaughan reported the results of laser treatment of supraglottic laryngeal cancer. Since then, laser surgery has developed rapidly, In some developed countries accounted for 30% to 50% of all laryngeal cancer surgery, showing an increasing trend year by year. The advantage of laryngeal laser surgery is less damage, good preservation, fast recovery, short operation time and low cost, while other reports show that laser surgery can maintain hemoglobin levels, is conducive to postoperative radiotherapy [2]. 1 surgical indications Due to differences in equipment technology and understanding, there is no standard indications for surgery. Theoretically, the exposed tissue under the laryngoscope can be excised with laser, while the cartilage frame can be preserved and the vertical partial laryngectomy and supraglottic resection can be completed [3]. However, some objective factors of