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目的分析深圳市龙岗区病毒性肝炎患者血清学分型监测结果。方法采集静脉血5ml分离血清,-20℃保存。每2个月用冷藏车或者冰瓶专人送至市疾病预防控制中心急性传染病防治科检验室。用酶联免疫吸附法(ELISA)检测抗-HAV-IgM、HBsAg、抗-HBs、抗-HBc、抗HBcIgM、抗-HCV、抗HEVIgM等。结果抗-HAV-IgM总阳性检出率为1.55%,其中仅2002年为5.19%,其余年均为0。HBsAg总阳性检出率为34.44%,HBsAg+抗-HBc总阳性检出率为34.13%,HBsAg+抗HBcIgM总阳性检出率为5.56%,抗-HBcIgM总阳性检出率为13.21%。抗-HEVIgM总阳性检出率为8.17%,波动在1.90%～38.46%之间。未分型即总未检出率39.96%,波动在16.67%～60.00%之间。结论乙、丙型型肝炎仍然是目前重点防治的传染病。戊型肝炎的防治已经刻不容缓。
Objective To analyze the serological typing results of patients with viral hepatitis in Longgang District, Shenzhen. Methods Blood samples were collected from 5ml venous blood and stored at -20 ℃. Every 2 months with a refrigerated truck or ice bottle sent to the Municipal Center for Disease Control and Prevention acute infectious disease prevention and control laboratory. Anti-HAV-IgM, HBsAg, anti-HBs, anti-HBc, anti-HBcIgM, anti-HCV, anti-HEVIgM and the like were detected by enzyme-linked immunosorbent assay (ELISA) Results The total positive detection rate of anti-HAV-IgM was 1.55%, of which only 5.19% in 2002 and 0 in other years. The total positive detection rate of HBsAg was 34.44%, the total positive detection rate of HBsAg + anti-HBc was 34.13%, the positive detection rate of HBsAg + anti HBcIgM was 5.56%, and the positive detection rate of anti-HBcIgM was 13.21%. The total positive detection rate of anti-HEVIgM was 8.17%, and the fluctuation ranged from 1.90% to 38.46%. Undifferentiated that is, the total undetected rate of 39.96%, fluctuations in 16.67% ~ 60.00% between. Conclusions B and C are still the most important infectious diseases. Hepatitis E prevention and control has been urgent.