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目的 分析ATA 2015版成人《甲状腺结节和分化型甲状腺癌诊治指南》(简称《指南》)所引用参考文献的特点.方法 利用Excel表格对2015版《指南》的参考文献按文献标题、发表时间、期刊区域等进行汇总分析,并与ATA 2009版《指南》比较.结果 2015版《指南》引用文献1078篇,年份跨度63年(1952至2015年),专业期刊172种,专业书籍8本.文献地域分布偏倚度大.与2009版《指南》相比,2015版《指南》引用新发表文献比例高.2015版《指南》也依据文献的科学证据强度对《指南》推荐条款进行分类,但新旧《指南》中高质量证据的推荐条款均少于50％.结论 2015版《指南》引用文献量多且广泛,但源文献地域差异大,高质量文献仍有不足.“,”Objective To interpret the major characteristics of literatures cited by 2015 ATA management guidelines for adult patients with thyroid nodules and DTC (2015 version).Methods The titles,datelines of the references,the medical specialties and regional distribution of the journals,and the definition of the scientific evidence rating for relevant references were extracted and analyzed.The data were roughly compared with those of 2009 revised ATA management guidelines for patients with thyroid nodules and DTC (2009 version).Results A total of 1 078 literatures,from 172 journals and 8 books,were cited by 2015 version,with 63 years spacing from 1952 to 2015.Extensive medical specialties were involved.The journals were world-wide distributed but the regional bias was obvious.Compared to the 2009 version,2015version adopted more recent literatures,and used more evidence rating for the recommendations.However,references with high-quality evidence were both less than 50％ in the two versions.Conclusion Huge amount of references with multi-specialties have been cited in 2015 version,however the regional distribution bias is distinctive and references with high-quality evidence are still insufficient.