遗传和一些环境因素已被证实与高血压的发病有关 ,但是最近的研究显示 ,原发性高血压患者常伴有脂代谢紊乱 ,葡萄糖耐量减低以及胰岛素抵抗。产生这些代谢紊乱原因认为部分是由于交感神经系统产生的儿茶酚胺 (ＣＯＡＭ)过多。ＣＯＡＭ作用于效应受体 ,促使心排血量增加 ,外周阻 Genetic and environmental factors have been shown to be associated with the development of hypertension, but recent studies have shown that patients with essential hypertension often have disorders of lipid metabolism, impaired glucose tolerance, and insulin resistance. The cause of these metabolic disorders is thought to be partly due to the excess of catecholamines (COAMs) produced by the sympathetic nervous system. COAM role in the effector, to promote increased cardiac output, peripheral resistance