论文部分内容阅读
目的分析缺血性脑卒中患者血清中超敏C-反应蛋白(hs-CRP)、妊娠相关蛋白A(PAPP-A)水平的异常情况。方法将212例缺血性脑卒中患者分为轻度梗死组98例,中度梗死组74例及重度梗死组40例。将106例健康观察者作为健康组,分别采用酶联免疫吸附试验(ELISA)法检测各组血清hs-CRP、PAPP-A水平。结果轻度梗死组、中度梗死者、重度梗死组3组较健康组血清hs-CRP、PAPP-A水平均具有显著性增高,差异均有统计学意义(P<0.05)。结论血清中hs-CRP、PAPP-A两者水平在缺血性脑卒中时均显著性地增高,均可用于缺血性脑卒中的辅助诊断及梗死程度预估。
Objective To analyze the abnormalities of serum hs-CRP and PAPP-A in patients with ischemic stroke. Methods A total of 212 ischemic stroke patients were divided into mild infarction group (n = 98), moderate infarction group (n = 74) and severe infarction group (n = 40). 106 healthy observers were selected as healthy group. Serum levels of hs-CRP and PAPP-A were detected by enzyme linked immunosorbent assay (ELISA). Results The levels of serum hs-CRP and PAPP-A in three groups of mild infarction group, moderate infarction group and severe infarction group were significantly higher than those in healthy group (P <0.05). Conclusions Serum levels of hs-CRP and PAPP-A both significantly increase in ischemic stroke, which can be used in the diagnosis of ischemic stroke and prediction of the degree of infarction.