目的分析柳州市强制戒毒所2007~2008年新入所吸毒人员的艾滋病(H IV)、梅毒(TP)感染情况,为进一步采取针对性干预措施提供依据。方法在2007年7月、2008年7月对新近入所不超过3个月的戒毒人员,采用随机抽样的方法,进行问卷调查和血清H IV、TP抗体检测。结果共调查293人,其中H IV感染者37人,TP感染者12人(其中5人混合感染H IV)。第一次注射吸毒平均年龄为(24.9±6.8)岁,承认有共用注射器吸毒史的50.2%,在最近一次注射吸毒时与他人共用针具的有28.3%,最近一个月注射吸毒时与他人共用针具的36.7%。最近1年内有商业性性行为的有25.3%,最近1次商业性性行为时安全套使用率为77.0%。最近一年10.6%发生过同性性行为,且28.0%出现过排尿痛或烧灼感、尿道/阴道分泌物异常、生殖器出现皮肤破损或增生物等性病相关症状的。结论柳州市戒毒所戒毒人群的高危行为发生较社区吸毒者严重,需要进一步在戒毒所内开展针对性宣传和干预,达到有效控制艾滋病在吸毒人群中传播及由吸毒人员向一般人群传播的目的。 Objective To analyze the prevalence of HIV and syphilis in new drug abusers from 2007 to 2008 in compulsory drug rehabilitation centers in Liuzhou City, and to provide basis for further targeted interventions. Methods In July 2007 and July 2008, the randomized sampling methods were used to conduct the questionnaire survey and the detection of serum H IV, TP antibodies to drug addicts newly admitted within 3 months. Results A total of 293 people were investigated, of which 37 were H IV infected and 12 were TP infected (5 were mixed with H IV). The average age of the first injection was (24.9 ± 6.8) years old, 50.2% of the people who shared the common history of drug abuse and 28.3% of the people who shared the same drug during the last injection and shared it with others during the last month of injecting drug use 36.7% of needle. 25.3% of the commercial sexual behaviors in the recent year and 77.0% in the last commercial sexual activity. In the most recent year, 10.6% had homosexual behaviors, and 28.0% had dysuria or burning sensation, abnormal urethral / vaginal secretions, genital skin lesions or proliferative diseases such as STD-related symptoms. Conclusions The high-risk behavior of drug addicts in Liuzhou City is more serious than that of drug addicts in community-based drug addicts. Therefore, it is necessary to carry out targeted publicity and interventions in drug addicts so as to effectively control the spread of AIDS among drug addicts and their transmission to the general population.