近年来,伤寒发病率有下降趋势,典型伤寒病例已较以往少见.鉴于抗生素、退热药和激素的广泛使用,致伤寒热型受上述因素影响而发生改变,血培养阳性率亦有所降低.由于轻症和不典型病例增多及伤寒病临床表现的复杂化和多样化,给诊断带来了困难,以致发生误诊已屡见不鲜.其误诊率自22%～30.9%不等.为探讨对伤寒病的诊断,现将我院1970～1986年经细菌培养和肥达氏反应确诊之伤寒病285例分析如下: In recent years, the incidence of typhoid fever has declined, the typical case of typhoid fever has been rare than in the past.Due to the widespread use of antibiotics, antipyretics and hormones, typhoid fever caused by the above factors change, the positive rate of blood culture also decreased Due to the increase of mild and atypical cases and the complicated and diversified clinical manifestations of typhoid fever, it has caused difficulties in diagnosis and misdiagnosis has not been uncommon.Its misdiagnosis rate ranges from 22% to 30.9% Disease diagnosis, now in our hospital from 1970 to 1986 by bacterial culture and Widal reaction diagnosed 285 cases of typhoid fever are as follows: