论文部分内容阅读
在格氏线虫Neoaplectana glaseri对小白鼠的安全测试中,经血液常规检查和组织切片观察,均未发现小白鼠有任何异常现象。但是,由于小白鼠个体小,有些测试项目如体温变化,血清中转氨酶含量测定等不易进行。另一方面,安全试验要求有不同种类的动物代表。所以,我们在进行了格氏线虫对小白鼠的安全测试后,又对家兔进行了敏感性测验。本文报道格氏线虫对家兔的敏感性试验结果。材料和方法供试线虫由实验室培养所得,经蒸馏水反复冲洗后稀释到所需浓度。从华南农学院家兔养殖场获得的健康家兔(体重1～1.5公斤)随机编组饲养观察测量体温,一星期后供试验。感染途径、线虫用量和实验动物数见表1。
In Neisseria gonorrhoeae safety tests on mice, routine blood tests and histological sections did not reveal any abnormalities in the mice. However, due to the small individual mice, some test items such as changes in body temperature, serum aminotransferase determination is not easy to carry out. On the other hand, safety tests require different kinds of animal representatives. So, after we carried out the safety test of the gerbils on the mice, we conducted the sensitivity test on the rabbits again. In this paper, the sensitivity of Grimes nematodes to rabbits test results. Materials and Methods The test nematodes were obtained from the laboratory culture, washed repeatedly with distilled water and diluted to the desired concentration. Healthy rabbits (weighing from 1 to 1.5 kg) obtained from rabbit farms in South China Agricultural College were randomly divided into groups and fed for observation to measure body temperature. One week later, they were tested. Infection route, nematode amount and number of experimental animals are shown in Table 1.