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目的分析颅骨骨巨细胞瘤的CT和MRI表现。方法收集8例经手术和病理证实的颅骨骨巨细胞瘤。全部病例均行CT和MRI检查(其中6例行增强CT检查,5例行增强MRI检查)。所有病例均行外科手术切除。术后2周,行放射治疗,剂量4500～6000cGy,时间为5～6周。结果CT显示不同程度的骨质破坏和钙化。大部分肿瘤边界清晰,MRIT1加权像呈低信号,T2加权像呈不均匀信号。T1加权像低信号区在T2加权像上随回波时间延长信号仍呈低信号而提示钙化。所有病例术后随访均无明显变化。结论CT能准确显示骨质破坏情况及钙化程度,MRI在显示病变的范围方面要优于CT,两者结合是诊断颅骨骨巨细胞瘤的最佳影像学检查方法。手术切除与术后放疗相结合是治疗颅骨骨巨细胞瘤较好的方法。
Objective To analyze the CT and MRI features of giant cell tumor of the skull. Methods Eight cases of giant cell tumor of the skull confirmed by surgery and pathology were collected. CT and MRI examinations were performed in all cases (6 of them underwent enhanced CT and 5 of them underwent enhanced MRI). All cases were surgically removed. After 2 weeks, radiation therapy was performed at a dose of 4500-6000 cGy for 5-6 weeks. Results CT showed varying degrees of bone destruction and calcification. Most of the tumors have clear borders, low-weighted images of MITT1 weighted images, and non-uniform signals of T2-weighted images. The T1-weighted low-signal region is still low-signaled on the T2-weighted image as the echo-time prolongs the signal, suggesting calcification. All patients had no significant changes after follow-up. Conclusion CT can accurately show bone destruction and calcification. MRI is superior to CT in displaying the extent of lesions. The combination of the two is the best imaging method for the diagnosis of giant cell tumor of the skull. Combining surgical resection with postoperative radiotherapy is a better method for treating giant cell tumor of the skull.