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目的探讨阿托伐他汀和辛伐他汀治疗高血压患者合并2型糖尿病和血脂异常的效果。方法高血压、血脂异常合并2型糖尿病患者102例,按抽签方法分为观察组与对照组,每组51例。两组常规降糖治疗,再分别加阿托伐他汀和辛伐他汀治疗,观察两组总胆固醇、血脂等变化。结果治疗后,两组的TC、TG、LDL-C、HDL-C均有明显变化,本组与治疗前比较差异有统计学意义(P<0.05),观察组各值接近正常范围,比对照组更有优势,两组差异有统计学意义(P<0.05)。结论阿托伐他汀控制血压和调脂作用更好。
Objective To investigate the effect of combination of atorvastatin and simvastatin on type 2 diabetes mellitus and dyslipidemia in hypertensive patients. Methods 102 cases of type 2 diabetes mellitus with hypertension and dyslipidemia were divided into observation group and control group by lottery method, with 51 cases in each group. Two groups of conventional hypoglycemic treatment, and then were treated with atorvastatin and simvastatin, total cholesterol, blood lipid and other changes were observed. Results After treatment, the levels of TC, TG, LDL-C and HDL-C in both groups changed significantly. The difference between this group and before treatment was statistically significant (P <0.05). The values of the observation group were close to the normal range, Group more advantages, the difference between the two groups was statistically significant (P <0.05). Conclusions Atorvastatin has better control of blood pressure and lipid-lowering effect.