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正常的甲状腺功能状态是维持女性生殖能力的一个重要因素;甲状腺激素直接或间接参与调节女性生殖功能。甲状腺机能障碍会影响性激素结合球蛋白(SHBG)和催乳素(PRL)水平,从而改变类固醇激素代谢和下丘脑-垂体-卵巢轴的功能,导致凝血功能障碍和各种生殖问题,如月经紊乱、排卵障碍、不孕、流产、早产等。甲状腺机能障碍通过适当的临床干预可能恢复正常的月经周期,并改善生殖功能。
Normal thyroid function status is an important factor in maintaining female reproductive capacity; thyroid hormone directly or indirectly involved in regulating female reproductive function. Hypothyroidism affects levels of sex hormone-binding globulin (SHBG) and prolactin (PRL), alters steroid hormone metabolism and hypothalamic-pituitary-ovarian axis function, leading to coagulopathies and a variety of reproductive problems such as menstrual disorders, Ovulation disorders, infertility, miscarriage, premature birth and so on. Thyroid dysfunction may resume normal menstrual cycle with proper clinical intervention and improve reproductive function.