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目的:探讨联合应用骨化三醇及钙剂对老年性骨质疏松(senile osteoporosis,SO)的防治效果。方法:根据随机数字表将2014年4月-2015年4月在我院接受治疗的112例SO患者分为实验组及对照组,各56例,前者给予骨化三醇+钙剂,后者给予钙剂;6个月后,比较两组骨密度及治疗总有效率。结果:治疗6个月后,实验组显效率及治疗总有效率分别为51.79%、89.29%,均显著高于对照组23.21%、50.00%(P<0.05)。实验组L2-4侧位、脚踝、股骨颈骨密度均显著高于对照组(P<0.05)。结论:联合应用骨化三醇及钙剂治疗SO可有效改善患者骨密度,提高临床疗效。
Objective: To explore the preventive and therapeutic effects of calcitriol and calcium on senile osteoporosis (SO). Methods: According to the random number table, 112 SO patients treated in our hospital from April 2014 to April 2015 were divided into experimental group and control group, 56 cases in each. The former was given calcitriol and calcium, the latter Given calcium; 6 months later, compared two groups of bone mineral density and total effective rate. Results: Six months after treatment, the markedly effective rate and the total effective rate of the experimental group were 51.79% and 89.29%, respectively, which were significantly higher than those of the control group (23.21% and 50.00%, P <0.05). The BMD of L2-4 in the experimental group was significantly higher than that in the control group (P <0.05). Conclusion: The combination of calcitriol and calcium can effectively improve the bone mineral density and improve the clinical curative effect.