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目的分析比较妇女绝经期前后子宫内膜癌的临床与病理特点,为临床治疗提供理论依据。方法本院2005年1月至2010年12月经病理确诊、住院治疗且有完整资料的子宫内膜癌68例,其中绝经组34例,未绝经组34例,对其临床和病理特点进行分析。结果未绝经组子宫内膜样腺癌的比例较高,病理分期未绝经组的Ⅰ期比例较低,但2组差异无统计学意义;未绝经组患者特殊病理类型较少,组织分级低,G1级所占比例较高,肌层浸润深度较低,宫颈受累较少,5年生存率明显高于绝经组,差异有统计学意义。结论绝经前子宫内膜癌组织分级低,深肌层浸润少见,预后较好,生存率高。
Objective To analyze and compare the clinical and pathological characteristics of women with and without endometrial cancer before and after menopause to provide a theoretical basis for clinical treatment. Methods From January 2005 to December 2010, 68 cases of endometrial cancer were diagnosed as pathologically, hospitalized and had complete data, including 34 cases in the menopause group and 34 cases in the non-menopausal group. The clinical and pathological features were analyzed. Results The proportion of endometrial adenocarcinoma in the non-menopausal group was higher than that in the non-menopausal group, but there was no significant difference between the two groups (P> 0.05). There were less special pathological types, less histological grade, Gl level higher proportion, lower myometrial invasion, less cervical involvement, 5-year survival was significantly higher than the menopause group, the difference was statistically significant. Conclusion The premenopausal endometrial carcinoma has low grade and deep myometrial infiltration with a good prognosis and high survival rate.