论文部分内容阅读
垂体腺瘤的内分泌诊断其目的在于:通过腺瘤激素自发性异常分泌检查,早期发现及鉴别腺瘤与非肿瘤性病变,有无向鞍上发展及疗效判断等.本文参照当前有关文献,综述如下:一、生长激素(GH)细胞腺瘤:临床表现为肢端肥大症或巨人症.正常GH值在低血糖,氨基酸,应激及运动时增高,而高血糖时则抑制.与血中游离脂肪酸有关,青年浅睡期明显增高,各种活性氨基酸影响显著.上述因素在检查时甚为重要.A血浆GH基础值:正常5ng/ml以下,本症多超过10ng/ml以上.B对抑制正常人GH物质的反应:1.葡萄糖:口服50～100gm,正常人如增高也在5ng/ml以下,本症多增高,部分减少者也在5ng/ml以上.
The purpose of endocrine diagnosis of pituitary adenomas is to detect abnormal adenoma hormones, early detection and differential diagnosis of adenomas and non-neoplastic lesions, whether to develop to the saddle, and to evaluate therapeutic effects. This article refers to the current literature, review As follows: First, growth hormone (GH) cell adenomas: clinical manifestations of acromegaly or gigantism. Normal GH values in hypoglycemia, amino acids, stress and exercise increased, while high blood sugar is inhibited. With blood With regard to free fatty acids, the young people’s sleeping time is significantly higher, and various active amino acids have a significant effect. The above factors are very important at the time of examination. A Plasma GH basal value: normal 5 ng/ml or less, the disease more than 10 ng/ml or more. Inhibition of normal human GH response: 1. Glucose: Oral 50 ~ 100gm, normal people such as increased in 5ng/ml or less, the disease increased more, some of the reduction was also 5ng/ml or more.