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目的:对阿奇霉素与热毒宁联合应用于儿童支原体肺炎的治疗效果加以探讨。方法:选取我院2014年12月至2015年12月收治的支原体肺炎患儿52例,将之随机分成观察组与对照组各26例。对照组患儿予以单纯阿奇霉素治疗,观察组患儿则在此基础上加用热毒宁进行治疗,对2组患者临床疗效、不良反应发生率、住院时间、咳嗽消失时间、退热时间等加以对比。结果:本研究观察组、对照组患儿临床治疗总有效率分别为96.2%与73.1%,对比差异有统计学意义(χ~2=5.318,P<0.05);观察组、对照组患儿不良反应发生率分别为11.5%与7.7%,对比差异无统计学意义(χ~2=0.221,P>0.05);观察组患儿在住院时间、咳嗽消失时间、退热时间等方面相比于对照组患儿均有显著优势,比差异有统计学意义(t=3.438,7.269,3.588,4.318,4.825,P<0.05)。结论:将热毒宁与阿奇霉素联合应用于支原体肺炎患儿的临床治疗可有效缩短其住院、退热、咳嗽、啰音消失等时间,促进临床疗效的极大提高,切无严重不良反应发生,故值得借鉴。
Objective: To investigate the therapeutic effect of azithromycin combined with Rendoxine in children with mycoplasma pneumonia. Methods: 52 cases of mycoplasma pneumonia admitted from December 2014 to December 2015 in our hospital were randomly divided into observation group and control group with 26 cases each. Children in the control group were treated with azithromycin alone, while those in the observation group were treated with Rendoxine on the basis of this treatment. Clinical efficacy, incidence of adverse reactions, length of hospital stay, disappearance of cough, and antipyretic time were all increased Compared. Results: The total effective rate of clinical treatment in observation group and control group was 96.2% and 73.1%, respectively, with significant difference (χ ~ 2 = 5.318, P <0.05). In observation group and control group, (Χ ~ 2 = 0.221, P> 0.05). Compared with the control group, the incidences of hospitalization, disappearance of cough and the time of fever were significantly lower in the observation group than those in the control group The children in group had significant advantages, the difference was statistically significant (t = 3.438,7.269,3.588,4.318,4.825, P <0.05). Conclusions: The clinical application of combination of heat toxicity and azithromycin in children with mycoplasma pneumonia can effectively shorten the hospitalization, fever, cough, rales and other disappearance time, and promote the clinical efficacy greatly increased, no serious adverse reactions, It is worth learning.