观察苦瓜果的不同成分对成年雄性大鼠生育力的影响。其中苦瓜粗制液可引起８３．４％的大鼠丧失生育力；附睾尾精子活力降低、畸形效增加；约７％～８％的曲细精管内易见多核巨细胞，并见晚期精子细胞有退变现象。停药２周后．生育力开始恢复，至第８周末已趋正常。表明苦瓜粗制液对雄性大鼠有较明显抗生育作用并具可逆性，而苦瓜提取物中的蛋白成分抗生育作用较差，非蛋白成分的作用极不明显。 To observe the effects of different components of bitter melon on the fertility of adult male rats. Among them, the bitter melon crude liquid can cause the loss of fertility in 83.4% of the rats; the sperm motility of epididymal tails decreased, the malformation effect increased; about 7% ~ 8% of the seminiferous tubules were easy to see multinucleated giant cells, and see late sperm cells Degenerate phenomenon. After 2 weeks withdrawal. Fertility began to recover and became normal at the end of the eighth week. Show that bitter melon crude solution on male rats have obvious anti-fertility and reversible, while the bitter melon extract of the protein composition of poor anti-fertility, the role of non-protein composition is not obvious.