We demonstrate the generation of supercontinuum (SC) of over 1350 nm by injecting 790-nm, 15-fs, 74-MHz optical pulses into a 183-mm-long microstructured fiber with combination core and random cladding. The maximum total power of SC is 73 mW with 290-mW pump power from 40* microscope objective. The wavelength and power ranging in SC as well as the polarization states and waveguide modes of the visible light can be tuned by adjusting the input end of MF. In particular, white light has been observed. To our knowledge, this is the first report of tunable properties in SC generation process using microstructured fiber with combination core and random cladding.