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作者在透射电镜下观察了大鼠精子发生过程中支持细胞（Ｓｅｒｔｏｌｉ细胞）中溶酶体的结构及分布的改变。结果Ｓｅｒｔｏｌｉ细胞中溶酶体数目多，在细胞中所处的位置有周期性变化，细胞中全部胞质和在基底部胞质中溶酶体的截面积占胞质截面积的比例在生精第ＶＩＩ阶段最大，近腔部溶酶体截面积占胞质截面积在第ＩＩ、ＩＸ阶段最小；Ｓｅｒｔｏｌｉ细胞总胞质和在基底部单位胞质截面积的溶酶体数在第ＶＩＩ阶段最大，近腔部单位胞质截面积溶酶体数在顶体期后几阶段最大，第ＩＸ阶段最小。Ｓｅｒｔｏｌｉ细胞溶酶体的周期性变化是与生精细胞相互影响、相互作用，也是精子连续正常发生的前提条件之一。
The authors observed the changes in the structure and distribution of lysosomes in Sertoli cells during spermatogenesis in rats under transmission electron microscope. Results Sertoli cells in the number of lysosomes in the cell where the location of cyclical changes in the cells in the cytoplasm and basal cell lysosomes in the cross-sectional area of the ratio of cytoplasmic cross-sectional area in the spermatogenesis The largest in stage VII, the near area cytoplasmic cross-sectional area of proximal cavities was the smallest in stages II and IX; the number of lysosomes in the total cytoplasm of Sertoli cells and the cytoplasmic cross-sectional area in basal ganglia was the largest in stage VII The number of cytoplasmic cross-section lysosomes in the proximal cavities was the largest in several stages after acrosometosis and the smallest in stage IX. Sertoli cell cycle changes in lysosomes and spermatogenic cells interact with each other, but also one of the preconditions for the normal sperm succession.