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目的:评价地塞米松预防计算机断层扫描(CT)增强扫描中应用非离子型碘对比剂所致不良反应的效果。方法:将郑州第六人民医院2015年6月至2016年6月收治的486例行CT增强扫描患者分为观察组与对照组,每组各243例,观察组患者于检查前给予静脉注射地塞米松,对照组患者则不给予使用任何药物,观察比较两组患者非离子型碘对比剂所致不良反应发生情况。结果:非离子型碘对比剂所致不良反应多为轻度,观察组患者检查后不良反应发生率为1.2%,低于对照组患者的8.2%,两组患者不良反应发生率比较,差异有统计学意义(P<0.05)。结论:CT增强扫描前使用地塞米松可有效预防非离子型碘对比剂所致不良反应的发生。
OBJECTIVE: To evaluate the efficacy of dexamethasone in preventing non-toxic iodine contrast-induced adverse reactions in computed tomography (CT) enhanced scans. Methods: 486 routine CT contrast-enhanced CT scan patients from June 2015 to June 2016 in Zhengzhou Sixth People’s Hospital were divided into observation group and control group, 243 cases in each group. Patients in observation group were given intravenous injection The patients in the control group were not given any drugs, and the adverse reactions caused by the non-ionic iodine contrast agent were observed and compared between the two groups. Results: Non-ionic iodine contrast agent-induced adverse reactions were mostly mild in the observation group of patients after the adverse reaction rate was 1.2%, 8.2% lower than the control group, the incidence of adverse reactions in both groups, the difference was Statistical significance (P <0.05). Conclusion: The use of dexamethasone before CT enhanced scan can effectively prevent the adverse reaction caused by nonionic iodine contrast agent.