一定剂量范围的γ射线可使机体在一定时间内免疫功能低下,并出现感染等一系列的并发症。白细胞介素-1（IL-1）主要是由单核巨噬细胞产生,研究发现它对多种免疫活性细胞有重要调节作用,并诱导这些细胞产生对肿瘤细胞的细胞毒活性。本研究采用MTT比色法,观察了重组人IL-1β（rhIL-1β）对γ射线照射小鼠淋巴细胞增殖的影响。 A certain dose range of gamma rays can make the body immune dysfunction within a certain period of time, and a series of complications such as infection. Interleukin-1 (IL-1) is mainly produced by mononuclear macrophages. It has been found that interleukin-1 (IL-1) plays an important regulatory role in a variety of immunocompetent cells and induces these cells to produce cytotoxic activity on tumor cells. In this study, the MTT assay was used to observe the effect of recombinant human IL-1β (rhIL-1β) on lymphocyte proliferation in γ-ray irradiated mice.