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目的 对支原体诱发的咳嗽变异性哮喘的治疗方法及相应的治疗效果进行研究探讨.方法 选择2012年10月至2013年10月诊断为支原体诱发的咳嗽变异性哮喘的80例患儿作为临床研究对象,随机将其分为对照组和观察组,每组40例.对照组在常规治疗的基础上给予雾化吸入糖皮质激素进行治疗,观察组在对照组的治疗基础上,给予静脉滴注红霉素治疗3d后,再静脉滴注阿奇霉素进行治疗.比较两组患儿的临床治疗总有效率和肺功能改善情况.结果 观察组临床治疗总有效率为95.0％,显著大于对照组,差异有统计学意义(P＜0.05).在肺功能改善方面,观察组第1秒用力肺活量、用力呼气流量均明显高于对照组,差异有统计学意义(P＜0.05).结论 静脉滴注红霉素和阿奇霉素结合雾化吸入糖皮质激素对于支原体诱发的咳嗽变异性哮喘具有很好的临床治疗效果.“,”Objective To investigate the treatment of cough variant asthma induced by mycoplasma and the treatment effect.Methods From October 2012 to October 2013,80 children diagnosed as mycoplasma-induced asthma were chosen as clinical study objects.These children were randomly divided into control group and observation group.Forty cases in control group,on the basis of conventional treatment were given nebulized corticosteroid treatment.Forty cases in the observation group on the basis of the treatment,were given intravenous erythromycin 3d,then intravenous azithromycin for treatment.Comparison of the two groups of children with clinical efficiency and overall improvement in lung function.Results The total effective rate was 95.0％ in observation group,which was significantly higher than that of the control group,the difference was statistically significant (P ＜ 0.05).Improvements in lung function,the observation group of children forced vital capacity in one second (FEV1),forced expiratory flow rate (PEFR) were significantly higher,and the difference was statistically significant(P ＜0.05).Conclusions Intravenous erythromycin and azithromycin combined nebulized corticosteroids for mycoplasma-induced cough variant asthma has a good clinical effect.