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目的:对胰岛素治疗妊娠期糖尿病的疗效及母婴风险进行研究探讨。方法:随机抽取2012年1月~2013年10月本院接诊的200例妊娠期糖尿病患者为研究对象,随机分为观察组、对照组,每组100例,对照组采取单一饮食疗法,观察组在对照组的基础上,增加胰岛素治疗,其中62例妊娠28周前应用胰岛素的产妇设为A组,其余设为B组。比较两组患者的分娩孕周、新生儿体重和母婴并发征。结果:观察组分娩孕周为(37.8±0.9)周显著低于对照组(38.1±1.1),二者比较差异显著(P<0.05),有统计学意义;在新生儿出生体重比较方面,二者无显著差异(P>0.05),在早产、高血压疾病、胎儿窘迫等,并发症方面,两组患者无显著性差异(P>0.05);观察组A组及对照组新生儿无低血糖发生,观察组B组新生儿低血糖3例(7.9%),与对照组比较差异显著(P<0.05)。结论:适时应用胰岛素能维持妊娠期血糖正常,有效规避母婴风险。
Objective: To study the effect of insulin on gestational diabetes mellitus and maternal and infant risk. Methods: A total of 200 cases of gestational diabetes admitted to our hospital from January 2012 to October 2013 were randomly divided into observation group and control group, with 100 cases in each group. The control group was given single dietary therapy and observation group In the control group, based on the increase in insulin treatment, of which 62 cases of pregnant women before 28 weeks of pregnancy insulin as A group, the rest set to B group. Pregnancy, birth weight and maternal and infant complications were compared between the two groups. Results: Compared with the control group (37.8 ± 0.9), the gestational age of observation group was significantly lower than that of the control group (38.1 ± 1.1) (P <0.05), and there was significant difference between the two groups There was no significant difference between the two groups (P> 0.05). There was no significant difference between the two groups in preterm birth, hypertension, fetal distress and other complications (P> 0.05) (P <0.05). There were 3 cases (7.9%) of neonatal hypoglycemia observed in group B, which was significantly different from the control group (P <0.05). Conclusion: The timely application of insulin can maintain normal blood glucose during pregnancy and effectively avoid the risk of mother-infant.