双氯苯眯唑是β-代1-苯乙-亚胺唑(β-substit-uted 1-phenety1-imidazole)。1969年首次报告它对大多数致病性真菌、腐物寄生性真菌及固紫阳性细菌有广谱抗菌作用,近来又成功地用来治疗皮肤及女阴真菌感染。本文报告24例临床上明显的口腔念珠菌感染患者,从口腔粘膜35例次均培养出白色念珠菌。大多数患者有各种类型的急性白血病,并接受细胞抑制剂(cytostatics)、强的松龙和抗菌 Dichloroprene is β-substit-uted 1-phenety1-imidazole. It was first reported in 1969 as having a broad spectrum of antibacterial activity against most pathogenic fungi, parasitic fungi and solid-violet-positive bacteria and has recently been used successfully to treat skin and vaginal infections. This article reports 24 cases of clinically significant oral Candida infections in 35 oral mucosa were average cultures of Candida albicans. Most patients have various types of acute leukemia, and receive cytostatics, prednisolone, and antibacterials