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目的探究新生儿重症监护病房医院感染的危险因素。方法对本院2014年1月-2016年1月NICU收治患儿发生医院感染的273例及同期收治的300例非感染患儿作为研究对象,对NICU医院感染的单因素及多因素进行logistic回归分析。结果单因素结果提示出生体重、分娩方式、胎龄、Apgar评分、羊水浑浊、侵入式治疗、PICC计划拔管、穿刺时间、新生儿窒息、机械通气、静脉营养及穿刺次数是导致NICU新生患儿感染的影响因素;logistic回归分析结果提示分娩方式、羊水浑浊、侵入性治疗、肠外营养、胎龄及低体重是导致NICU患儿感染的独立危险因素。结论分娩方式、羊水浑浊、侵入性治疗、肠外营养、胎龄及低体重是导致NICU医院感染的独立危险因素,应加强对相关独立因素监控,降低NICU医院感染率。
Objective To explore the risk factors of nosocomial infection in neonatal intensive care unit. Methods From January 2014 to January 2016, 273 hospitalized NICU patients in our hospital and 300 non-infected children in the same period were enrolled in this study. Logistic regression was performed on single and multiple factors of NICU nosocomial infection analysis. Results Univariate results suggested that birth weight, mode of delivery, gestational age, Apgar score, amniotic fluid opacity, invasive treatment, PICC extubation, puncture time, neonatal asphyxia, mechanical ventilation, Logistic regression analysis showed that mode of delivery, amniotic fluid opacity, invasive treatment, parenteral nutrition, gestational age and low body weight were the independent risk factors of NICU infection. Conclusions Mode of delivery, amniotic fluid opacity, invasive treatment, parenteral nutrition, gestational age and low body weight are the independent risk factors of NICU infection. Monitoring of relevant independent factors should be strengthened to reduce NICU infection rate.