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顺铂是最有效的抗肿瘤药物之一,但其大剂量应用时,会引起多种副作用,如肝毒性等。从肉豆蔻Myristica fragrans Houtt.中提取的肉豆蔻木脂素具有抗氧化活性,并引起肝酶活性的改变。研究了肉豆蔻木脂素对顺铂诱导的小鼠肝毒性的保护作用及其可能的作用机制。将肉豆蔻木脂素溶于玉
Cisplatin is one of the most effective anti-tumor drugs, but when used in large doses, it can cause various side effects such as hepatotoxicity. Myristyl lignans extracted from Myristica fragrans Houtt. have antioxidant activity and cause changes in liver enzyme activity. The protective effect of myristiside lipopolysaccharide on cisplatin-induced hepatotoxicity in mice and its possible mechanism were studied. Dissolve nutmeg in nutmeg