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目的:观察早期侧脑室穿刺引流治疗隐球脑膜炎的临床效果.方法:对8例隐球菌脑膜炎行早期侧脑室穿刺引流,引流时间视脑压而定,最长引流两周.6例对照.以隐球菌镜检计数,墨汁染色,隐球菌培养隐球菌阴性时间及临床症状的改善情况和是否并发脑积水为观察指标.结果:治疗组头痛、视力障碍及意识改善均较对照组为优,两月后前者轻度视力障碍1例,后者轻度视力障碍1例,重度视力障碍1例.对照组两性霉素-B鞘内注射诱发脑疝1例.治疗组无一并发脑积水,而对照组治疗过程中2例脑积
Objective: To observe the clinical effect of early lateral ventricle puncture and drainage for the treatment of cryptococcal meningitis.Methods: Eight patients with cryptococcal meningitis underwent early lateral ventriculoventricular perfusion, the time of drainage was determined by intracranial pressure and the longest drainage was performed for two weeks. The number of cryptococcal microscopic examination, ink stain, Cryptococcus neoformans culture time and the improvement of clinical symptoms and whether or not complicated with hydrocephalus were observed.Results: The treatment group headache, visual impairment and improvement of consciousness than the control group , One case of mild visual impairment in the former two months later, one case of mild visual impairment and one case of severe visual impairment in one case.Among the cases of intrathecal injection of amphotericin-B in the control group, Water, while the control group during treatment of 2 cases of brain volume