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本文报道60例食管癌作超分割分段放射治疗的前瞻性研究。分析了1、2年生存率、食管X片检查以及胸痛缓解、进食改善时间和体重变化情况,并观察了放射反应,提示超分割分段加常规分割放射的方法治疗病变长度大于5cm的晚期食管癌,对加速肿瘤退缩,提高近期疗效有一定的优越性,且没有增加放射反应和并发症,值得深入研究,积累更丰富的资料,以便作出最后的评价。本文井对超分割放射的理论依据作了探讨。
This article reports a prospective study of 60 patients with esophageal cancer undergoing hyperfractionated segmented radiotherapy. The 1-year and 2-year survival rates, esophageal X-ray examinations, chest pain relief, eating improvement time, and body weight changes were analyzed. The radiological response was observed. Hyperfractionated segmented and conventional segmentation radiotherapy was suggested to treat advanced esophageal lesions with a lesion length greater than 5 cm. Cancer has certain advantages in accelerating tumor regression and improving the short-term curative effect, and it does not increase radiation reactions and complications. It is worthy of in-depth study to accumulate more abundant data in order to make a final evaluation. This paper discusses the theoretical basis for the hyperfractionation radiation.