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目的研究老年实体肿瘤患者对化疗的耐受性。方法回顾性分析我科老年实体肿瘤35例与中青年实体肿瘤47例化疗后的毒副反应,根据世界卫生组织(WHO)抗癌药物常见毒副反应分级标准评定毒副反应程度,并将老年实体肿瘤与中青年实体肿瘤患者化疗后毒副反应进行比较。结果老年实体肿瘤患者化疗后骨髓抑制、恶心呕吐、神经毒性反应与中青年患者比较,差异无统计学意义(χ2=3.0408~8.5446,P>0.05)。结论老年实体肿瘤患者能够耐受多数化疗的毒性反应。
Objective To study the chemotherapy tolerance of elderly solid tumor patients. Methods Retrospective analysis of 35 cases of old solid tumors in our department and 47 cases of solid tumors in young and middle-aged patients after chemotherapy toxicity, according to the World Health Organization (WHO) common toxicological classification of toxic and side effects to assess the degree of toxicity, and the elderly Solid tumors and solid tumors in young patients after chemotherapy compared side effects. Results There was no significant difference in bone marrow suppression, nausea, vomiting and neurotoxicity after chemotherapy between elderly patients with solid tumors and middle-aged patients (χ2 = 3.0408 ~ 8.5446, P> 0.05). Conclusion Elderly solid tumor patients can tolerate the toxicity of most chemotherapy.