糜蛋白酶系自牛或猪胰腺中提取的一种蛋白分解酶,可以消化脓液、积血、坏死组织,起到净化创面、抗感染、消肿作用。临床上广泛应用于输卵管再通术、呼吸道炎症的雾化吸入治疗等。近年来,偶有应用糜蛋白酶引起严重过敏反应的报道。我科在应用糜蛋白酶行雾化吸入治疗过程中发生哮喘发作2例,报告如下。 Chymotrypsin is a proteolytic enzyme extracted from bovine or porcine pancreas, which can digest pus, hemorrhage and necrotic tissue, play a role of purifying the wound, resisting infection and swelling. Clinical widely used in tubal recanalization, respiratory inflammation of inhalation therapy. In recent years, occasional application of chymotrypsin cause serious allergic reactions reported. My department in the application of chymotrypsin inhalation therapy in the course of asthma attack occurred in 2 cases, the report is as follows.