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鸟氨酸氨基甲酰转移酶(OCT)是哺乳类动物鸟氨酸循环中重要的酶,主要存于肝细胞线粒体。生化测定表明胚胎期大鼠肝组织中OCT活性很低,出生后随年龄而升高,生后四周达正常水平。关于大鼠发育过程中肝组织OCT的组织化学变化迄今未见报道。本文进行这方面的探讨。
Ornithine carbamoyltransferase (OCT) is an important enzyme in the ornithine cycle of mammals and mainly exists in hepatocyte mitochondria. Biochemical assays showed that OCT activity in the liver tissue of embryonic rats is very low, increases with age after birth and reaches normal levels in the fourth week after birth. Histochemical changes of hepatic tissue OCT during rat development have not been reported. This article discusses in this area.