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目的比较分析2008—2011四年间各类标本检出致病菌的菌群分布以及药敏试验情况,研究其间是否存在趋势性变化,为本地区的院感防治及临床抗生素的使用等诊疗工作提供依据.方法按检出率分别统计2008—2011年每年所有检出细菌的大类分布及各自前十位的细菌名及所占百分比,比较分析其菌群分布变化情况及趋势.将细菌分为肠杆菌科类、非发酵菌类、革兰氏阳性球菌类三大类,并对其进行每年度的药敏情况分析.细菌鉴定及药敏试验采用全自动微生物分析仪.结果从大类上来看,检出细菌分布多以肠杆菌科细菌为主,其次为G+球菌,比例最小的是非发酵菌类细菌,但此类细菌所占比例从2008年的6.1%到2011年的12.6%,呈稳定上升趋势;几年中所检出占前十位的细菌大致稳定;三大类细菌的药敏试验结果保持相对稳定的状态,未发现呈现趋势性上升或下降的情况.结论近四年我院检出致病菌菌群分布未出现明显的趋势性改变,药敏耐药率也保持相对稳定状态.“,” Objective: To analyze the bacterial distribution and drug sensitivity tests between 2008-2011,and provide basis for nosocomial infection prevetion and the use of antibiotics. Methods: Rate the pathogenic bacteria tested between 2008-2011 and classify such microorganisms into gram-positive cocci, no-fermentative bacteria and enterobacteriaceae. Comparatively analyze the top 10 species’ distribution and drug suscepbility. Results: The top pathogenic bacterial are enterobacteriaceae, gram-positive cocci, and no-fermentative bacteria, respectively. But the percentage of such pathogens rises from 6.1% in 2008 to 12.6% in 2011. The top ten and their suscepbility keep constant and no trend observed. Conclusion: The bacterial distribution of the pathogens tested keep stable and no trend is found in their suscepbility.