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目的探讨腹腔镜下子宫动脉栓塞术联合甲氨蝶呤注射治疗子宫角妊娠的临床疗效。方法选取2015年10月-2016年10月邵逸夫医院收治的70例子宫角妊娠患者为研究对象,按照随机数字表法分为观察组和对照组,各35例。两组患者均行腹腔镜下子宫角妊娠切除,对照组同时采用甲氨蝶呤肌内注射治疗,观察组在对照组基础上加用双侧子宫动脉栓塞术。对两组患者的手术情况、术后治疗效果以及并发症发生率情况进行比较分析。结果在手术情况方面,观察组患者的术中出血量、手术时间、住院天数均小于对照组,差异有统计学意义(P<0.05)。术后疗效,观察组患者h CG转阴时间、病灶清除时间、月经恢复时间均小于对照组,差异有统计学意义(P<0.05)。并发症发生率,观察组为5.71%,低于对照组的28.57%,组间比较差异有统计学意义(P<0.05)。结论子宫动脉栓塞术联合甲氨蝶呤可减少手术时间和术中出血量,提高手术的安全性和治疗效果,并能降低术后并发症的发生,有临床应用价值。
Objective To investigate the clinical efficacy of laparoscopic uterine arterial embolization combined with methotrexate in the treatment of uterine horn pregnancy. Methods Seventy patients with uterine horn pregnancy who were treated in Run Run Shaw Hospital from October 2015 to October 2016 were selected as study subjects and divided into observation group and control group according to the random number table. Two groups of patients underwent laparoscopic uterine horn pregnancy resection, while the control group was treated with intramuscular injection of methotrexate, the observation group in the control group based on the addition of bilateral uterine artery embolization. The two groups of patients with surgery, postoperative treatment and complication rates were compared. Results In terms of the operation, the amount of blood loss, operation time and hospitalization days in the observation group were all less than those in the control group, with statistical significance (P <0.05). The postoperative curative effect, h CG CG negative time, lesion clearance time and menstruation recovery time in the observation group were all less than those in the control group, the difference was statistically significant (P <0.05). The complication rate was 5.71% in the observation group and 28.57% in the control group, with significant difference between the two groups (P <0.05). Conclusion Uterine artery embolization combined with methotrexate can reduce the operation time and intraoperative blood loss, improve the safety of surgery and treatment, and can reduce the incidence of postoperative complications, and has clinical value.