黑色素细胞在正常情况下分散在皮肤、毛发、眼虹膜及脉络膜等器宫内。皮肤的黑色素细胞位于表皮基底细胞之间,无细胞间桥和张力原纤维,胞浆透亮,核小而色深,有长的胞浆树突(图1),能产生或制造黑色素。在某些病理情况下,例如由于黑色素细胞的增生或功能亢进等原因。所引起的良性或恶性的病变,种类较多,在病理诊断中常带来一定的困难,单用一般常规H.E.染色较难确诊,必须选择特异性强,操作较为方便的方法才行。按黑色素是一种蛋白衍生物,呈褐色 Melanocytes are normally dispersed in the uterus of the skin, hair, eye iris, and choroid. The skin’s melanocytes are located between the basal cells of the epidermis without intercellular bridges and tonic fibrils. The cytoplasm is translucent with small nuclei and deep color, with long cytoplasmic dendrites (Figure 1), which can produce or produce melanin. In some pathological conditions, for example due to hyperplasia or hyperfunction of melanocytes. Caused by benign or malignant lesions, there are many types, and it often brings certain difficulties in pathological diagnosis. It is difficult to diagnose with simple routine H.E. staining, and specific methods must be selected to facilitate the operation. Melanin is a protein derivative that is brown