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本文应用抗轮状病毒免疫牛初乳,对43例轮状病毒感染性腹泻患儿进行了治疗,同时对37例轮状病毒感染性腹泻患儿给予思密达治疗作为对照,以观察两组的治疗效果与大便排毒之间的关系,结果免疫初乳治疗组72小时止泻的总有效率为91％,大便病毒抗原转阴率为89％;而思密达组总有效率为41％,经治疗72小时腹泻仍不止22例,占59％,72小时大便病毒抗原仍阳性为61％。表明抗轮状病毒免疫牛初乳能有效地发挥其特异性中和病毒和抑制病毒的增殖,从而达到其治疗作用,思密达仅仅起到肠道粘膜的屏障保护作用,但不能特异性抑制病毒在肠腔细胞中的增殖。
In this paper, anti-rotavirus immune colostrum, 43 cases of rotavirus infection in children with diarrhea were treated, and 37 cases of rotavirus infection in children given smecta treatment as a control to observe the two groups Of the results of the treatment and the relationship between stool detoxification, the results of immune colostrum treatment group 72-hour anti-diarrhea total effective rate was 91%, stool virus antigen negative rate was 89%; while the Smectite group the total effective rate was 41% After 72 hours of treatment, diarrhea was still more than 22 cases (59%), and 72 hours of stool virus antigen was still positive (61%). The results showed that anti-rotavirus immune colostrum can effectively exert its specific neutralizing virus and inhibit the proliferation of virus so as to achieve its therapeutic effect. Smectite only plays a barrier protective role of intestinal mucosa but can not specifically inhibit Virus proliferation in intestinal cells.