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作者对手术切除大肠癌合并肝转移癌的34例(转移组)及无肝转移大肠癌的40例(对照组)的资料,依据日本“临床·病理大肠癌处理规约”进行了临床病理学对比分析。结果表明淋巴结转移(N)、远处转移(P)各转移因子的分级转移组明显高于对照组(P<0.01);浆膜浸润(S)、静脉浸润(V)、淋巴管浸润(L)各浸润因子分级转移组亦明显高于对照组(P<0.01);转移组浸润方式infγ占79.4%,两组间差异极显著(P<0.01);癌原发部位转移组多见乙状结肠(41.9%),对照组则多见右半结肠(55%),两组间差异极显著(P<0.01);组织学分型两组间差异显著(P<0.05);肉眼分型及肿瘤最大直径面积两组间则无显著差异(P>0.05)。依据本组结果作者提出了术中彻底切除转移癌灶,应用术中实时B超的临床病理学指标及术后癌肝转移的半定量预测方法并应用模糊术学原理绘出预测曲线。
The authors compared the clinical data of 34 cases with colorectal cancer and liver metastases (metastasis group) and 40 cases without liver metastasis (control group) according to the Japanese “clinical and pathological colorectal cancer treatment protocol”. analysis. The results showed that lymph node metastasis (N) and distant metastasis (P) were significantly higher in the metastasis group than in the control group (P<0.01); serosal infiltration (S), venous infiltration (V), and lymphatic infiltration (L) The levels of invasive factors in the metastasis group were also significantly higher than those in the control group (P<0.01); infγ in the metastasis group accounted for 79.4%, with significant difference between the two groups (P<0.01); The sigmoid colon (41.9%) was more common in the metastatic group and the right colon (55%) was more common in the control group (P<0.01). The histological type was significantly different between the two groups (P<0.01). P<0.05); There was no significant difference between the two groups (P>0.05). According to the results of this group, the authors proposed a complete resection of metastatic lesions during surgery, the use of real-time B-ultrasound clinical pathological indicators and postoperative liver cancer metastasis semi-quantitative prediction methods and application of fuzzy theory of surgery to draw a prediction curve.