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[目的]观察补阳还五汤+血府逐瘀汤联合西药治疗肿瘤血管新生疗效。[方法]使用随机平行对照方法,将229例住院患者按掷骰子法简单随机分为两组。对照组97例化疗放疗。治疗组132例补阳还五汤(黄芪生125g,当归尾6g,赤芍5g,地龙、川芎、红花、桃仁各3g);血府逐瘀汤(当归、生地各9g,桃仁12g,红花9g,枳壳、赤芍各6g,柴胡、甘草各3g,桔梗、川芎各4.5g,牛膝10g),1剂/d,水煎200m L,早晚口服;西药治疗同对照组。连续治疗7d为1疗程。观测临床症状、肿瘤增殖、不良反应。连续治疗4疗程,判定疗效。[结果]治疗组显效36例,有效68例,无效28例,总有效率78.79%。对照组显效25例,有效41例,无效31例,总有效率68.04%。治疗组疗效优于对照组(P<0.05)。[结论]补阳还五汤+血府逐瘀汤联合西药治疗肿瘤血管新生,疗效满意,无副作用,值得推广。
[Objective] To observe the therapeutic effect of Buyang Huanwu Decoction + Xuefu Zhuyu Decoction combined with western medicine on tumor angiogenesis. [Methods] A total of 229 inpatients were randomly divided into two groups according to the method of dice rolling using randomized parallel method. The control group of 97 cases of chemotherapy and radiotherapy. The treatment group 132 cases of Buyang Huanwu Decoction (Astragalus 125g, Angelica tail 6g, red peony 5g, earthworm, Chuanxiong, safflower, peach kernel each 3g); Xuefuzhuyu Decoction (Angelica, habitat each 9g, peach kernel 12g, Safflower 9g, Citrus aurantium, red peony root 6g, Bupleurum, licorice 3g, Campanulaceae, Chuanxiong each 4.5g, Achyranthes 10g), 1 / d, decoction 200m L, sooner or later oral; Western medicine treatment with the control group. Continuous treatment 7d for a course of treatment. Observed clinical symptoms, tumor proliferation, adverse reactions. Continuous treatment of 4 courses to determine the efficacy. [Result] The treatment group was effective in 36 cases, effective in 68 cases, ineffective in 28 cases, the total effective rate was 78.79%. The control group markedly effective in 25 cases, effective in 41 cases, 31 cases were ineffective, the total effective rate was 68.04%. The treatment group was better than the control group (P <0.05). [Conclusion] Buyang Huanwu Decoction + Xuefu Zhuyu Decoction combined with Western medicine in the treatment of tumor angiogenesis has satisfactory curative effect and no side effects and is worth popularizing.