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目的研究新辅助化疗联合保乳术治疗乳腺癌的临床疗效。方法将2009年5月-2011年5月早期乳腺癌患者84例分为两组各42例,观察组采用新辅助化疗联合保乳术治疗,对照组采用根治术治疗,术后均行化疗,均随访2年,比较两组临床疗效。结果观察组手术时间、术中出血量、并发症发生率、住院天数等均明显少于对照组,组间差异有统计学意义(P<0.05);两组患者2年复发率及远处转移率比较无统计学差异(P>0.05)。结论新辅助化疗联合保乳术治疗乳腺癌的手术时间、术中出血量、手术并发症发生率、住院天数等均明显低于乳腺癌改良根治术,患者满意度高,值得临床推广。
Objective To study the clinical effect of neoadjuvant chemotherapy and breast-conserving surgery on breast cancer. Methods 84 patients with early breast cancer from May 2009 to May 2011 were divided into two groups of 42 patients. The patients in the observation group were treated with neoadjuvant chemotherapy plus breast-conserving surgery while the control group were treated with radical surgery. All patients underwent chemotherapy, All cases were followed up for 2 years, and the clinical efficacy was compared between the two groups. Results The operation time, intraoperative blood loss, complication rate and days of hospitalization in the observation group were significantly less than those in the control group (P <0.05). The two-year recurrence rate and distant metastasis No significant difference in rates (P> 0.05). Conclusion Neoadjuvant chemotherapy combined with breast-conserving surgery for breast cancer surgery time, intraoperative blood loss, the incidence of complications, hospitalization days are significantly lower than modified radical mastectomy, patients with high satisfaction, is worth clinical promotion.