论文部分内容阅读
目的探讨不同孕期妊娠妇女血清铁蛋白(SF)水平的变化及临床意义。方法 823例行产前检查的不同孕期妊娠妇女定为观察组,根据孕期不同可分为早孕组(139例)、中孕组(193例)、晚孕组(491例),选择52例非妊娠妇女为对照组,分别检测血清铁蛋白含量、血红蛋白、红细胞分布宽度。结果随早、中、晚孕期的发展,血清铁蛋白含量、血红蛋白浓度呈明显下降趋势,以血清铁蛋白下降趋势最为明显。三组孕妇红细胞分布宽度比较差异无统计学意义(P>0.05);早孕组血清铁蛋白含量、血红蛋白浓度与对照组比较差异无统计学意义(P>0.05);中孕、晚孕组血清铁蛋白含量、血红蛋白浓度均低于对照组、早孕组,差异具有统计学意义(P<0.05);晚孕组血清铁蛋白含量、血红蛋白浓度低于中孕组,差异具有统计学意义(P<0.05)。观察组孕妇中检出120例缺铁性贫血,早孕组、中孕组、晚孕组各3例、14例和103例;321例铁蛋白缺乏,早孕组、中孕组、晚孕组各4例、16例和305例。随着孕周的增加,铁蛋白缺乏的患病率越来越高,贫血患病率也随之升高,差异均有统计学意义(P<0.05)。结论在不同孕期孕妇体内铁存储量不足,其中中期、晚期孕妇以缺铁为主要表现,应及时对他们进行铁剂的补充,保证胎儿的营养和正常发育,减少缺铁性贫血的发生有着重要的意义。
Objective To investigate the changes and clinical significance of serum ferritin (SF) levels in pregnant women of different gestations. Methods Eight hundred and seventy pregnant women of different gestational ages who underwent prenatal examinations were enrolled as observation group. According to the different stages of pregnancy, they were divided into three groups: early pregnancy group (139 cases), middle pregnancy group (193 cases) and late pregnancy group (491 cases) Pregnant women as control group, respectively, detection of serum ferritin content, hemoglobin, red blood cell distribution width. Results With the development of early, middle and late pregnancy, the levels of serum ferritin and hemoglobin decreased significantly, and the decline of serum ferritin was the most obvious. There was no significant difference in the distribution width of erythrocytes between the three groups (P> 0.05). There was no significant difference in serum ferritin and hemoglobin between the first trimester and the control group (P> 0.05) (P <0.05). The levels of serum ferritin and hemoglobin in the late pregnancy group were lower than those in the second trimester group (P <0.05), and the difference was statistically significant ). In the observation group, 120 cases of iron deficiency anemia were detected in pregnant women, including 3 cases in early pregnancy group, middle pregnancy group and late pregnancy group, 14 cases and 103 cases in each group, 321 cases of ferritin deficiency, early pregnancy group, middle pregnancy group and late pregnancy group 4 cases, 16 cases and 305 cases. With the increase of gestational age, the prevalence of ferritin deficiency is getting higher and higher, and the prevalence of anemia also increases, the differences were statistically significant (P <0.05). Conclusions In different pregnant women, the amount of iron stored in the pregnant women is not enough. Among them, the middle and late pregnant women take the iron deficiency as the main performance, they should be supplemented with iron timely to ensure the nutrition and normal development of the fetus and reduce the occurrence of iron deficiency anemia Meaning.