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目的观察川芎嗪联合还原型谷胱甘肽治疗酒精性肝病的临床疗效。方法随机抽取2010年1月至2012年1月我院消化内科门诊及住院的酒精性肝病患者78例,分成两组,对照组39例,仅采取常规治疗;治疗组39例,在对照组常规治疗的基础上,增加川芎嗪、还原型谷胱甘肽药物,两组正规治疗1月后,观察临床症状及肝功能中ALT、AST、GGT、TBIL等各项指标的变化。结果治疗组总有效率及肝功能的指标恢复程度明显优于对照组,且无明显的不良反应。结论川芎嗪联合还原型谷胱甘肽治疗酒精性肝病,需在严格戒酒及祛除病因的基础上,成为一种有效、安全的治疗方法,值得在临床上推广。
Objective To observe the clinical efficacy of ligustrazine combined with reduced glutathione for the treatment of alcoholic liver disease. Methods From January 2010 to January 2012, 78 patients with alcoholic liver disease in our hospital were divided into two groups, control group, 39 cases, only conventional treatment; treatment group, 39 cases in the control group routine On the basis of treatment, add ligustrazine, reduced glutathione drugs, regular treatment of two groups after 1 month, observe the clinical symptoms and liver function ALT, AST, GGT, TBIL and other indicators of change. Results The total effective rate and the index of liver function recovery in the treatment group were significantly better than those in the control group, with no obvious adverse reactions. Conclusion Ligustrazine combined with reduced glutathione for the treatment of alcoholic liver disease, need to be strict on alcohol and eliminate the cause of disease, based on an effective and safe treatment, it is worth in the clinical promotion.