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组织器官纤维化主要表现以胶原为主要成分的细胞外基质(extra cellular matrix,ECM)的过度沉积,并导致正常组织器官结构破坏及功能丧失。长期以来人们进行了大量的抗纤维化药物研究工作,虽然取得了一定成果,但是治疗效果并不理想。随着中药抗纤维化的细胞及分子机制的研究逐步
The fibrosis of tissues and organs mainly shows the excessive deposition of extra cellular matrix (ECM) with collagen as the main component, and leads to the destruction of normal tissue and organ structure and loss of function. For a long time, people have carried out a lot of anti-fibrotic drug research work. Although they have achieved certain results, the treatment effect is not satisfactory. With the study of the cellular and molecular mechanisms of anti-fibrosis of traditional Chinese medicine